Overview
Active Immunity is a twin-stick bullet-hell roguelite from Dylpickle Studios, set inside the human body. Something has slipped past the skin, and you are what the body sends back. You pick an immune cell, drop into infected tissue, and hold the line across 25 escalating waves of bacteria, viruses, fungi, parasites and worse. It launched on November 12, 2026 for PC, with English and Dutch language support.
Highlights
- Each immune cell plays differently, with its own fire pattern, stats and special ability. The Natural Killer Cell opens the roster as a glass cannon that answers a crowd with a 20-bullet radial burst.
- Progression is tied to survival: take a cell to wave 10 to unlock the next one, so the roster grows as you learn the bullet patterns.
- Beyond the campaign, an endless mode asks how long you last once the main fight is cleared. Single-player, online co-op and local co-op are all listed.
Who It's For
Fans of dense bullet patterns and build-crafting roguelites will feel at home weaving through infected tissue and stacking upgrades into a build that feels unfair. The biological theme gives the genre a fresh skin, and the cell-unlock loop rewards players who push each run a little further.
Game Info
Developer and publisher: Dylpickle Studios. Genres: Action, Indie. Release: November 12, 2026. Steam user tags include Action Roguelike, Bullet Hell, Roguelite, 2D and Controller. Pricing and user reception are best checked on the latest Steam listing.
