This article covers Synology Diskstation DS1621+ DiskStation DS1621+?NAS?W125846548 (DiskStation DS1621+?NAS AMD Ryzen?V1500B).
Overview
The Synology DiskStation DS1621+ is a 6-bay desktop NAS powered by an AMD Ryzen V1500B processor. Compared to its predecessor DS1618+, it delivers 174% higher 4K random read IOPS and 76% faster sequential write speeds. It comes with 4GB of DDR4 ECC memory, expandable up to 32GB, ensuring data integrity for critical workloads. This NAS is designed for data storage, sharing, and backup in small-to-medium businesses and creative environments. Dual built-in M.2 NVMe slots allow SSD caching without occupying drive bays, turbocharging HDD arrays by over 20x. You can also scale up to 16 drives by connecting two DX517 expansion units.
Connectivity & Compatibility
The DS1621+ features four Gigabit LAN ports with support for link aggregation and failover. A PCIe slot lets you add a 10GbE SFP+ or RJ-45 NIC for instant bandwidth upgrades. On the front, there are two USB 3.2 Gen 1 ports, and on the back, one eSATA port for external storage expansion. It supports hot-swappable 3.5-inch SATA HDDs/SSDs and 2.5-inch SATA SSDs. The file system can be Btrfs or ext4, and you can choose from various RAID levels including Synology Hybrid RAID (SHR).
Product Info
Released in November 2020, the DS1621+ sits in the mid-to-high-end NAS segment. In Japan, it retails for around ¥338,800 on . The package includes the NAS unit, power adapter, Ethernet cable, and quick installation guide. Synology provides a 3-year warranty. Positioned for SMBs and power users, the DS1621+ combines an AMD Ryzen V1500B CPU with ECC memory for reliable performance. The DiskStation Manager (DSM) OS offers a rich ecosystem of applications for backup, virtualization, and multimedia.
Best Use Cases
IT administrators in small-to-medium businesses: Use it as a file server or backup target for multiple clients. The Active Backup suite can protect Windows PCs, servers, and virtual machines. For heavy virtualization or database workloads, consider the higher-end DS1821+. Creative professionals (photographers, videographers): Store large media files and access them from multiple editing workstations. Adding a 10GbE card makes 4K/8K video editing feasible. SSD caching is recommended for direct editing. * Users focused on data protection: Snapshot Replication and Hyper Backup provide versioning and off-site backup. Btrfs automatically checks data integrity to guard against bit rot. However, a single NAS is still a single point of failure, so maintain additional backups to another NAS or cloud.
Product Disclosure (Amazon)
- Manufacturer: Synology
- Seller: New Oriental Technology
- Fulfilled by: New Oriental Technology
- ASIN: B08JH22W42
- Note: This article covers a manufacturer-made product based on Amazon listing details.





